Systematic Dissection of the Sequence Determinants of Gene 3’ End Mediated Expression Control

The 3’end genomic region encodes a wide range of regulatory process including mRNA stability, 3’ end processing and translation. Here, we systematically investigate the sequence determinants of 3’ end mediated expression control by measuring the effect of 13,000 designed 3’ end sequence variants on...

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Detalles Bibliográficos
Autores principales: Shalem, Ophir, Sharon, Eilon, Lubliner, Shai, Regev, Ifat, Lotan-Pompan, Maya, Yakhini, Zohar, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398552/
https://www.ncbi.nlm.nih.gov/pubmed/25875337
http://dx.doi.org/10.1371/journal.pgen.1005147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398552/
https://www.ncbi.nlm.nih.gov/pubmed/25875337
http://dx.doi.org/10.1371/journal.pgen.1005147

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