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The Role of Excitotoxic Programmed Necrosis in Acute Brain Injury
Excitotoxicity involves the excessive release of glutamate from presynaptic nerve terminals and from reversal of astrocytic glutamate uptake, when there is excessive neuronal depolarization. N-methyl-d-aspartate (NMDA) receptors, a subtype of glutamate receptor, are activated in postsynaptic neurons...
Autor principal: | Fujikawa, Denson G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398818/ https://www.ncbi.nlm.nih.gov/pubmed/25893083 http://dx.doi.org/10.1016/j.csbj.2015.03.004 |
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