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Evaluation of phosphopeptide enrichment strategies for quantitative TMT analysis of complex network dynamics in cancer-associated cell signalling

Defining alterations in signalling pathways in normal and malignant cells is becoming a major field in proteomics. A number of different approaches have been established to isolate, identify and quantify phosphorylated proteins and peptides. In the current report, a comparison between SCX prefractio...

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Detalles Bibliográficos
Autores principales: Lombardi, Benedetta, Rendell, Nigel, Edwards, Mina, Katan, Matilda, Zimmermann, Jasminka Godovac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. on behalf of the European Proteomics Association (EuPA) 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398868/
https://www.ncbi.nlm.nih.gov/pubmed/25893165
http://dx.doi.org/10.1016/j.euprot.2015.01.002