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The Paf1 complex represses small RNA-mediated epigenetic gene silencing

RNA interference (RNAi) refers to the ability of exogenously introduced double-stranded RNA (dsRNA) to silence expression of homologous sequences. Silencing is initiated when the enzyme Dicer processes the dsRNA into small interfering RNAs (siRNAs). Small RNA molecules are incorporated into Argonaut...

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Detalles Bibliográficos
Autores principales: Kowalik, Katarzyna Maria, Shimada, Yukiko, Flury, Valentin, Stadler, Michael Beda, Batki, Julia, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398878/
https://www.ncbi.nlm.nih.gov/pubmed/25807481
http://dx.doi.org/10.1038/nature14337