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MicroRNA-23b* targets proline oxidase, a mitochondrial tumor suppressor protein in renal cancer

Proline oxidase (POX) is a novel mitochondrial tumor suppressor, which can suppress proliferation and induce apoptosis through the generation of reactive oxygen species (ROS) and decreasing hypoxia inducible factor (HIF) signaling. Recent studies have demonstrated the absent expression of POX in hum...

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Detalles Bibliográficos
Autores principales: Liu, W, Zabirnyk, O, Wang, H, Shiao, Y-H, Nickerson, M L, Khalil, S, Anderson, L M, Perantoni, A O, Phang, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398970/
https://www.ncbi.nlm.nih.gov/pubmed/20562915
http://dx.doi.org/10.1038/onc.2010.237