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MicroRNA-23b* targets proline oxidase, a mitochondrial tumor suppressor protein in renal cancer
Proline oxidase (POX) is a novel mitochondrial tumor suppressor, which can suppress proliferation and induce apoptosis through the generation of reactive oxygen species (ROS) and decreasing hypoxia inducible factor (HIF) signaling. Recent studies have demonstrated the absent expression of POX in hum...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398970/ https://www.ncbi.nlm.nih.gov/pubmed/20562915 http://dx.doi.org/10.1038/onc.2010.237 |