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Genome-wide Identification of IRF1 Binding Sites Reveals Extensive Occupancy at Cell Death Associated Genes

IRF1 is a transcription factor involved in interferon signaling and has been shown to harbor tumor suppressor activity. In order to comprehensively identify pathways regulated by IRF1, we used chromatin immunoprecipitation followed by massive-parallel sequencing (ChIP-seq) to evaluate the gene targe...

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Detalles Bibliográficos
Autores principales: Rettino, Alessandro, Clarke, Nicole M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398980/
https://www.ncbi.nlm.nih.gov/pubmed/25893139
http://dx.doi.org/10.4172/2157-2518.S6-009