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The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) prevents the cell from lysing and protects the fungus against environmental stress conditions. Because it is absent in humans...

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Detalles Bibliográficos
Autores principales: Valiante, Vito, Macheleidt, Juliane, Föge, Martin, Brakhage, Axel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399325/
https://www.ncbi.nlm.nih.gov/pubmed/25932027
http://dx.doi.org/10.3389/fmicb.2015.00325