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Flexibility of short ds-DNA intercalated by a dipyridophenazine ligand

We use Förster Resonant Energy Transfer (FRET) in order to measure the increase of flexibility of short ds-DNA induced by the intercalation of dipyridophenazine (dppz) ligand in between DNA base pairs. By using a DNA double strand fluorescently labeled at its extremities, it is shown that the end-to...

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Detalles Bibliográficos
Autores principales: Jia, Fuchao, Despax, Stéphane, Münch, Jean-Pierre, Hébraud, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399336/
https://www.ncbi.nlm.nih.gov/pubmed/25932461
http://dx.doi.org/10.3389/fchem.2015.00025