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Titration of biologically active amyloid–β seeds in a transgenic mouse model of Alzheimer's disease

Experimental evidence in animal models suggests that misfolded Amyloid-β (Aβ) spreads in disease following a prion-like mechanism. Several properties characteristics of infectious prions have been shown for the induction of Aβ aggregates. However, a detailed titration of Aβ misfolding transmissibili...

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Detalles Bibliográficos
Autores principales:	Morales, Rodrigo, Bravo-Alegria, Javiera, Duran-Aniotz, Claudia, Soto, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399520/ https://www.ncbi.nlm.nih.gov/pubmed/25879692 http://dx.doi.org/10.1038/srep09349

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