Metformin Suppresses Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-+Lepr(db)/+Lepr(db) Mice

Obesity and related metabolic disorders, such as diabetes mellitus, raise the risk of liver carcinogenesis. Metformin, which is widely used in the treatment of diabetes, ameliorates insulin sensitivity. Metformin is also thought to have antineoplastic activities and to reduce cancer risk. The presen...

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Detalles Bibliográficos
Autores principales: Ohno, Tomohiko, Shimizu, Masahito, Shirakami, Yohei, Baba, Atsushi, Kochi, Takahiro, Kubota, Masaya, Tsurumi, Hisashi, Tanaka, Takuji, Moriwaki, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399835/
https://www.ncbi.nlm.nih.gov/pubmed/25879666
http://dx.doi.org/10.1371/journal.pone.0124081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399835/
https://www.ncbi.nlm.nih.gov/pubmed/25879666
http://dx.doi.org/10.1371/journal.pone.0124081

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