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Inhibition of Histone Deacetylases Facilitates Extinction and Attenuates Reinstatement of Nicotine Self-Administration in Rats

Chromatin remodelling is integral to the formation of long-term memories. Recent evidence suggests that histone modification may play a role in the persistence of memories associated with drug use. The present series of experiments aimed to examine the effect of histone deacetylase (HDAC) inhibition...

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Detalles Bibliográficos
Autores principales: Castino, Matthew R., Cornish, Jennifer L., Clemens, Kelly J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399837/
https://www.ncbi.nlm.nih.gov/pubmed/25880762
http://dx.doi.org/10.1371/journal.pone.0124796