Molecular Subtypes in Stage II-III Colon Cancer Defined by Genomic Instability: Early Recurrence-Risk Associated with a High Copy-Number Variation and Loss of RUNX3 and CDKN2A

OBJECTIVE: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. METHODS: We sought to investigate various molecular subtypes defined by instability at microsatellites (MSI), changes in methylation patter...

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Detalles Bibliográficos
Autores principales: Berg, Marianne, Nordgaard, Oddmund, Kørner, Hartwig, Oltedal, Satu, Smaaland, Rune, Søreide, Jon Arne, Søreide, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399912/
https://www.ncbi.nlm.nih.gov/pubmed/25879218
http://dx.doi.org/10.1371/journal.pone.0122391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399912/
https://www.ncbi.nlm.nih.gov/pubmed/25879218
http://dx.doi.org/10.1371/journal.pone.0122391

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