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Digital Detection of Multiple Minority Mutants and Expression Levels of Multiple Colorectal Cancer-Related Genes Using Digital-PCR Coupled with Bead-Array

To simultaneously analyze mutations and expression levels of multiple genes on one detection platform, we proposed a method termed “multiplex ligation-dependent probe amplification–digital amplification coupled with hydrogel bead-array” (MLPA–DABA) and applied it to diagnose colorectal cancer (CRC)....

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Detalles Bibliográficos
Autores principales: Huang, Huan, Li, Shuo, Sun, Lizhou, Zhou, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399940/
https://www.ncbi.nlm.nih.gov/pubmed/25880764
http://dx.doi.org/10.1371/journal.pone.0123420