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Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase

Impaired glucose tolerance characterized by postprandial hyperglycemia, which occurs frequently in elderly persons and represents an important preliminary step in diabetes mellitus, poses an independent risk factor for the development of atherosclerosis. Endothelial cellular senescence is reported t...

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Detalles Bibliográficos
Autores principales: Maeda, Morihiko, Hayashi, Toshio, Mizuno, Natsumi, Hattori, Yuichi, Kuzuya, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400006/
https://www.ncbi.nlm.nih.gov/pubmed/25879533
http://dx.doi.org/10.1371/journal.pone.0123169