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Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase
Impaired glucose tolerance characterized by postprandial hyperglycemia, which occurs frequently in elderly persons and represents an important preliminary step in diabetes mellitus, poses an independent risk factor for the development of atherosclerosis. Endothelial cellular senescence is reported t...
Autores principales: | Maeda, Morihiko, Hayashi, Toshio, Mizuno, Natsumi, Hattori, Yuichi, Kuzuya, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400006/ https://www.ncbi.nlm.nih.gov/pubmed/25879533 http://dx.doi.org/10.1371/journal.pone.0123169 |
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