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The Serotype Distribution among Healthy Carriers before Vaccination Is Essential for Predicting the Impact of Pneumococcal Conjugate Vaccine on Invasive Disease

Pneumococcal conjugate vaccines (PCVs) have substantially reduced morbidity and mortality of pneumococcal disease. The impact of the 7-valent PCV on all-serotype invasive pneumococcal disease (IPD) among children was reported to vary between high-income countries. We investigate the ability to predi...

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Detalles Bibliográficos
Autores principales: Flasche, Stefan, Le Polain de Waroux, Olivier, O’Brien, Katherine L., Edmunds, W. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400047/
https://www.ncbi.nlm.nih.gov/pubmed/25879748
http://dx.doi.org/10.1371/journal.pcbi.1004173