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Accumulation of an Endogenous Tryptophan-Derived Metabolite in Colorectal and Breast Cancers
Tumor immune escape mechanisms are being regarded as suitable targets for tumor therapy. Among these, tryptophan catabolism plays a central role in creating an immunosuppressive environment, leading to tolerance to potentially immunogenic tumor antigens. Tryptophan catabolism is initiated by either...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400104/ https://www.ncbi.nlm.nih.gov/pubmed/25881064 http://dx.doi.org/10.1371/journal.pone.0122046 |