Accumulation of an Endogenous Tryptophan-Derived Metabolite in Colorectal and Breast Cancers

Tumor immune escape mechanisms are being regarded as suitable targets for tumor therapy. Among these, tryptophan catabolism plays a central role in creating an immunosuppressive environment, leading to tolerance to potentially immunogenic tumor antigens. Tryptophan catabolism is initiated by either...

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Detalles Bibliográficos
Autores principales: Puccetti, Paolo, Fallarino, Francesca, Italiano, Antoine, Soubeyran, Isabelle, MacGrogan, Gaetan, Debled, Marc, Velasco, Valerie, Bodet, Dominique, Eimer, Sandrine, Veldhoen, Marc, Prendergast, Georges C., Platten, Michael, Bessede, Alban, Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400104/
https://www.ncbi.nlm.nih.gov/pubmed/25881064
http://dx.doi.org/10.1371/journal.pone.0122046

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