APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective

Chronic glial activation and neuroinflammation induced by the amyloid‐β peptide (Aβ) contribute to Alzheimer's disease (AD) pathology. APOE4 is the greatest AD‐genetic risk factor; increasing risk up to 12‐fold compared to APOE3, with APOE4‐specific neuroinflammation an important component of t...

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Detalles Bibliográficos
Autores principales: Tai, Leon M., Ghura, Shivesh, Koster, Kevin P., Liakaite, Vaiva, Maienschein‐Cline, Mark, Kanabar, Pinal, Collins, Nicole, Ben‐Aissa, Manel, Lei, Arden Zhengdeng, Bahroos, Neil, Green, Stefan J., Hendrickson, Bill, Van Eldik, Linda J., LaDu, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400246/
https://www.ncbi.nlm.nih.gov/pubmed/25689586
http://dx.doi.org/10.1111/jnc.13072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400246/
https://www.ncbi.nlm.nih.gov/pubmed/25689586
http://dx.doi.org/10.1111/jnc.13072

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