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EphA Receptors Form a Complex with Caspase-8 to Induce Apoptotic Cell Death

EphA7 has been implicated in the regulation of apoptotic cell death in neural epithelial cells. In this report, we provide evidence that EphA7 interacts with caspase-8 to induce apoptotic cell signaling. First, a pull-down assay using biotinylated ephrinA5-Fc showed that EphA7 co-precipitated with w...

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Detalles Bibliográficos
Autores principales: Lee, Haeryung, Park, Sunjung, Kang, Young-Sook, Park, Soochul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400310/
https://www.ncbi.nlm.nih.gov/pubmed/25855521
http://dx.doi.org/10.14348/molcells.2015.2279