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The Histone H3K9 Demethylase Kdm3b Is Required for Somatic Growth and Female Reproductive Function

Kdm3b is a Jumonji C domain-containing protein that demethylates mono- and di-methylated lysine 9 of histone H3 (H3K9me1 and H3K9me2). Although the enzyme activity of Kdm3b is well characterized in vitro, its genetic and physiological function remains unknown. Herein, we generated Kdm3b knockout (Kd...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoliang, Chen, Xian, Zhou, Suoling, Liao, Lan, Jiang, Rui, Xu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400382/
https://www.ncbi.nlm.nih.gov/pubmed/25892958
http://dx.doi.org/10.7150/ijbs.11849