Cargando…
The Histone H3K9 Demethylase Kdm3b Is Required for Somatic Growth and Female Reproductive Function
Kdm3b is a Jumonji C domain-containing protein that demethylates mono- and di-methylated lysine 9 of histone H3 (H3K9me1 and H3K9me2). Although the enzyme activity of Kdm3b is well characterized in vitro, its genetic and physiological function remains unknown. Herein, we generated Kdm3b knockout (Kd...
Autores principales: | Liu, Zhaoliang, Chen, Xian, Zhou, Suoling, Liao, Lan, Jiang, Rui, Xu, Jianming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400382/ https://www.ncbi.nlm.nih.gov/pubmed/25892958 http://dx.doi.org/10.7150/ijbs.11849 |
Ejemplares similares
-
Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors
por: Liu, Zhaoliang, et al.
Publicado: (2015) -
The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland
por: Qin, Li, et al.
Publicado: (2017) -
Transcriptional repression of ANGPT1 by histone H3K9 demethylase KDM3B
por: Han, Arim, et al.
Publicado: (2015) -
Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer
por: Wang, Hui-Yi, et al.
Publicado: (2019) -
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
por: Zhang, Qing-Jun, et al.
Publicado: (2018)