Cargando…
Increased expression of renal TRPM6 compensates for Mg(2+) wasting during furosemide treatment
BACKGROUND: Furosemide is a loop diuretic, which blocks the Na(+), K(+), 2Cl(−) cotransporter (NKCC2) in the thick ascending limb of Henle (TAL). By diminishing sodium (Na(+)) reabsorption, loop diuretics reduce the lumen-positive transepithelial voltage and consequently diminish paracellular transp...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400563/ https://www.ncbi.nlm.nih.gov/pubmed/26069797 http://dx.doi.org/10.1093/ckj/sfs140 |