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Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway
The KDM4 family of lysine demethylases consists of five members, KDM4A, -B and -C that demethylate H3K9me2/3 and H3K36me2/3 marks, while KDM4D and -E demethylate only H3K9me2/3. Recent studies implicated KDM4 proteins in regulating genomic instability and carcinogenesis. Here, we describe a previous...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400592/ https://www.ncbi.nlm.nih.gov/pubmed/25770186 http://dx.doi.org/10.1242/bio.201410991 |