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RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility

The postnatal mammalian ovary contains the primary follicles, each comprising an immature oocyte surrounded by a layer of somatic granulosa cells. Oocytes reach meiotic and developmental competence via folliculogenesis. During this process, the granulosa cells proliferate massively around the oocyte...

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Detalles Bibliográficos
Autores principales: Li, Huaibiao, Moll, Jürgen, Winkler, Anne, Frappart, Lucien, Brunet, Stéphane, Hamann, Jana, Kroll, Torsten, Verlhac, Marie-Hélène, Heuer, Heike, Herrlich, Peter, Ploubidou, Aspasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400598/
https://www.ncbi.nlm.nih.gov/pubmed/25750434
http://dx.doi.org/10.1242/bio.201410892