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MicroRNA-302/367 Cluster Governs hESC Self-Renewal by Dually Regulating Cell Cycle and Apoptosis Pathways

miR-302/367 is the most abundant miRNA cluster in human embryonic stem cells (hESCs) and can promote somatic cell reprogramming. However, its role in hESCs remains poorly understood. Here, we studied functional roles of the endogenous miR-302/367 cluster in hESCs by employing specific TALE-based tra...

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Detalles Bibliográficos
Autores principales: Zhang, Zhonghui, Hong, Yuanfan, Xiang, Di, Zhu, Pei, Wu, Elise, Li, Wen, Mosenson, Jeffrey, Wu, Wen-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400607/
https://www.ncbi.nlm.nih.gov/pubmed/25801506
http://dx.doi.org/10.1016/j.stemcr.2015.02.009