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A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing

We present a non-invasive method to characterize the function of pluripotent stem-cell-derived cardiomyocytes based on video microscopy and image analysis. The platform, called Pulse, generates automated measurements of beating frequency, beat duration, amplitude, and beat-to-beat variation based on...

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Detalles Bibliográficos
Autores principales: Maddah, Mahnaz, Heidmann, Julia D., Mandegar, Mohammad A., Walker, Chase D., Bolouki, Sara, Conklin, Bruce R., Loewke, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400609/
https://www.ncbi.nlm.nih.gov/pubmed/25801505
http://dx.doi.org/10.1016/j.stemcr.2015.02.007