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Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs

Human embryonic stem cell (hESC)-derived pancreatic progenitor cells effectively reverse hyperglycemia in rodent models of type 1 diabetes, but their capacity to treat type 2 diabetes has not been reported. An immunodeficient model of type 2 diabetes was generated by high-fat diet (HFD) feeding in S...

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Detalles Bibliográficos
Autores principales: Bruin, Jennifer E., Saber, Nelly, Braun, Natalie, Fox, Jessica K., Mojibian, Majid, Asadi, Ali, Drohan, Campbell, O’Dwyer, Shannon, Rosman-Balzer, Diana S., Swiss, Victoria A., Rezania, Alireza, Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400611/
https://www.ncbi.nlm.nih.gov/pubmed/25801507
http://dx.doi.org/10.1016/j.stemcr.2015.02.011