The Polycomb Group Protein L3MBTL1 Represses a SMAD5-Mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells

Epigenetic regulation of key transcriptional programs is a critical mechanism that controls hematopoietic development, and, thus, aberrant expression patterns or mutations in epigenetic regulators occur frequently in hematologic malignancies. We demonstrate that the Polycomb protein L3MBTL1, which i...

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Detalles Bibliográficos
Autores principales: Perna, Fabiana, Vu, Ly P., Themeli, Maria, Kriks, Sonja, Hoya-Arias, Ruben, Khanin, Raya, Hricik, Todd, Mansilla-Soto, Jorge, Papapetrou, Eirini P., Levine, Ross L., Studer, Lorenz, Sadelain, Michel, Nimer, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400644/
https://www.ncbi.nlm.nih.gov/pubmed/25754204
http://dx.doi.org/10.1016/j.stemcr.2015.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400644/
https://www.ncbi.nlm.nih.gov/pubmed/25754204
http://dx.doi.org/10.1016/j.stemcr.2015.02.003

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