The PI3K Pathway Balances Self-Renewal and Differentiation of Nephron Progenitor Cells through β-Catenin Signaling

Nephron progenitor cells differentiate to form nephrons during embryonic kidney development. In contrast, self-renewal maintains progenitor numbers and premature depletion leads to impaired kidney function. Here we analyze the PI3K pathway as a point of convergence for the multiple pathways that are...

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Detalles Bibliográficos
Autores principales: Lindström, Nils Olof, Carragher, Neil Oliver, Hohenstein, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400645/
https://www.ncbi.nlm.nih.gov/pubmed/25754203
http://dx.doi.org/10.1016/j.stemcr.2015.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400645/
https://www.ncbi.nlm.nih.gov/pubmed/25754203
http://dx.doi.org/10.1016/j.stemcr.2015.01.021

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