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The PI3K Pathway Balances Self-Renewal and Differentiation of Nephron Progenitor Cells through β-Catenin Signaling

Nephron progenitor cells differentiate to form nephrons during embryonic kidney development. In contrast, self-renewal maintains progenitor numbers and premature depletion leads to impaired kidney function. Here we analyze the PI3K pathway as a point of convergence for the multiple pathways that are...

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Detalles Bibliográficos
Autores principales:	Lindström, Nils Olof, Carragher, Neil Oliver, Hohenstein, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400645/ https://www.ncbi.nlm.nih.gov/pubmed/25754203 http://dx.doi.org/10.1016/j.stemcr.2015.01.021

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