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A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition
Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from epiblasts of postimplantation mouse embryos, and thus provide a useful model for studying “primed” pluripotent states. Here, we devised a simple and robust technique to derive high-quality EpiSCs using an inhibitor of WNT secretion...
Autores principales: | Sugimoto, Michihiko, Kondo, Masayo, Koga, Yumiko, Shiura, Hirosuke, Ikeda, Rieko, Hirose, Michiko, Ogura, Atsuo, Murakami, Ayumi, Yoshiki, Atsushi, Chuva de Sousa Lopes, Susana M., Abe, Kuniya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400648/ https://www.ncbi.nlm.nih.gov/pubmed/25818811 http://dx.doi.org/10.1016/j.stemcr.2015.02.014 |
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