Cargando…

Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

Colinear HOX expression during hindbrain and spinal cord development diversifies and assigns regional neural phenotypes to discrete rhombomeric and vertebral domains. Despite the precision of HOX patterning in vivo, in vitro approaches for differentiating human pluripotent stem cells (hPSCs) to post...

Descripción completa

Detalles Bibliográficos
Autores principales: Lippmann, Ethan S., Williams, Clay E., Ruhl, David A., Estevez-Silva, Maria C., Chapman, Edwin R., Coon, Joshua J., Ashton, Randolph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400649/
https://www.ncbi.nlm.nih.gov/pubmed/25843047
http://dx.doi.org/10.1016/j.stemcr.2015.02.018