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KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we systematically assessed cellular and molecular ha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400650/ https://www.ncbi.nlm.nih.gov/pubmed/25772473 http://dx.doi.org/10.1016/j.stemcr.2015.02.004 |