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KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency

As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we systematically assessed cellular and molecular ha...

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Detalles Bibliográficos
Autores principales: Kim, Shin-Il, Oceguera-Yanez, Fabian, Hirohata, Ryoko, Linker, Sara, Okita, Keisuke, Yamada, Yasuhiro, Yamamoto, Takuya, Yamanaka, Shinya, Woltjen, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400650/
https://www.ncbi.nlm.nih.gov/pubmed/25772473
http://dx.doi.org/10.1016/j.stemcr.2015.02.004