Type I IFN induced IL1-Ra expression in hepatocytes is mediated by activating STAT6 through the formation of STAT2: STAT6 heterodimer

The biological activities of type I interferons (IFNs) are mediated by their binding to a heterodimer receptor complex (IFNAR1 and IFNAR2), resulting in the activation of the JAK (JAK1 and TYK2)-STAT (1, 2, 3, 5 isotypes) signalling pathway. Although several studies have indicated that IFN-α and IFN...

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Detalles Bibliográficos
Autores principales: Wan, Lei, Lin, Cheng-Wen, Lin, Ying-Ju, Sheu, Jim JC, Chen, Bing-Hung, Liao, Chiu-Chu, Tsai, Yuhsin, Lin, Wei-Yong, Lai, Chih-Ho, Tsai, Fuu Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401122/
https://www.ncbi.nlm.nih.gov/pubmed/18494930
http://dx.doi.org/10.1111/j.1582-4934.2008.00143.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401122/
https://www.ncbi.nlm.nih.gov/pubmed/18494930
http://dx.doi.org/10.1111/j.1582-4934.2008.00143.x

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