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Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cells

We recently demonstrated original anti-tumor effects of zoledronic acid (Zol) on osteosarcoma cell lines independently of their p53 and Rb status. The present study investigated the potential Zol-resistance acquired by osteosarcoma cells after prolonged treatment. After 12 weeks of culture in the pr...

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Detalles Bibliográficos
Autores principales: Ory, B, Moriceau, G, Trichet, V, Blanchard, F, Berreur, M, Rédini, F, Rogers, M, Heymann, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401135/
https://www.ncbi.nlm.nih.gov/pubmed/18494934
http://dx.doi.org/10.1111/j.1582-4934.2008.00141.x