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Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

Recent data suggest that endothelial progenitor cells (EPCs) are involved in recanalizing venous thrombi. We examined the impact of a fibrin network, and particularly of adsorbed thrombin, on EPCs derived from cord blood CD34(+) cells. Fibrin networks generated in microplates by adding CaCl(2) to pl...

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Detalles Bibliográficos
Autores principales: Smadja, David M, Basire, Agnès, Amelot, Aymeric, Conte, Aurélie, Bièche, Ivan, Le Bonniec, Bernard F, Aiach, Martine, Gaussem, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401136/
https://www.ncbi.nlm.nih.gov/pubmed/18494938
http://dx.doi.org/10.1111/j.1582-4934.2008.00161.x