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Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities
Multiple genetic and environmental factors are likely to contribute to the development of Alzheimer's disease (AD). The most important known risk factor for AD is presence of the E4 isoform of apolipoprotein E (apoE). Epidemiological studies demonstrated that apoE4 carriers have a higher risk a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401287/ https://www.ncbi.nlm.nih.gov/pubmed/18205697 http://dx.doi.org/10.1111/j.1582-4934.2007.00130.x |