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Structural Effects of Protein Aging: Terminal Marking by Deamidation in Human Triosephosphate Isomerase
Deamidation, the loss of the ammonium group of asparagine and glutamine to form aspartic and glutamic acid, is one of the most commonly occurring post-translational modifications in proteins. Since deamidation rates are encoded in the protein structure, it has been proposed that they can serve as mo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401446/ https://www.ncbi.nlm.nih.gov/pubmed/25884638 http://dx.doi.org/10.1371/journal.pone.0123379 |