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Store-Operated Ca(2+) Entry Plays a Role in HMGB1-Induced Vascular Endothelial Cell Hyperpermeability

AIMS: Endothelial dysfunction, including increased endothelial permeability, is considered an early marker for atherosclerosis. High-mobility group box 1 protein (HMGB1) and extracellular Ca2+ entry, primarily mediated through store-operated Ca2+ entry (SOCE), are known to be involved in increasing...

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Detalles Bibliográficos
Autores principales: Zou, Mengchen, Dong, Hangming, Meng, Xiaojing, Cai, Chunqing, Li, Chenzhong, Cai, Shaoxi, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401536/
https://www.ncbi.nlm.nih.gov/pubmed/25884983
http://dx.doi.org/10.1371/journal.pone.0123432