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miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naïve CD4(+) T Cells
Upon TCR stimulation by peptide-MHC complexes, CD4(+) T cells undergo activation and proliferation. This process will ultimately culminate in T-cell differentiation and the acquisition of effector functions. The production of specific cytokines by differentiated CD4(+) T cells is crucial for the gen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401545/ https://www.ncbi.nlm.nih.gov/pubmed/25884400 http://dx.doi.org/10.1371/journal.pone.0125311 |