miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naïve CD4(+) T Cells

Upon TCR stimulation by peptide-MHC complexes, CD4(+) T cells undergo activation and proliferation. This process will ultimately culminate in T-cell differentiation and the acquisition of effector functions. The production of specific cytokines by differentiated CD4(+) T cells is crucial for the gen...

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Detalles Bibliográficos
Autores principales: Reddycherla, Amarendra V., Meinert, Ines, Reinhold, Annegret, Reinhold, Dirk, Schraven, Burkhart, Simeoni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401545/
https://www.ncbi.nlm.nih.gov/pubmed/25884400
http://dx.doi.org/10.1371/journal.pone.0125311

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