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Interaction of the Antimicrobial Peptide Polymyxin B1 with Both Membranes of E. coli: A Molecular Dynamics Study

Antimicrobial peptides are small, cationic proteins that can induce lysis of bacterial cells through interaction with their membranes. Different mechanisms for cell lysis have been proposed, but these models tend to neglect the role of the chemical composition of the membrane, which differs between...

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Detalles Bibliográficos
Autores principales: Berglund, Nils A., Piggot, Thomas J., Jefferies, Damien, Sessions, Richard B., Bond, Peter J., Khalid, Syma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401565/
https://www.ncbi.nlm.nih.gov/pubmed/25885324
http://dx.doi.org/10.1371/journal.pcbi.1004180