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Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

Patterning of functional blood vessel networks is achieved by pruning of superfluous connections. The cellular and molecular principles of vessel regression are poorly understood. Here we show that regression is mediated by dynamic and polarized migration of endothelial cells, representing anastomos...

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Detalles Bibliográficos
Autores principales: Franco, Claudio A., Jones, Martin L., Bernabeu, Miguel O., Geudens, Ilse, Mathivet, Thomas, Rosa, Andre, Lopes, Felicia M., Lima, Aida P., Ragab, Anan, Collins, Russell T., Phng, Li-Kun, Coveney, Peter V., Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401640/
https://www.ncbi.nlm.nih.gov/pubmed/25884288
http://dx.doi.org/10.1371/journal.pbio.1002125