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Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression
Patterning of functional blood vessel networks is achieved by pruning of superfluous connections. The cellular and molecular principles of vessel regression are poorly understood. Here we show that regression is mediated by dynamic and polarized migration of endothelial cells, representing anastomos...
Autores principales: | Franco, Claudio A., Jones, Martin L., Bernabeu, Miguel O., Geudens, Ilse, Mathivet, Thomas, Rosa, Andre, Lopes, Felicia M., Lima, Aida P., Ragab, Anan, Collins, Russell T., Phng, Li-Kun, Coveney, Peter V., Gerhardt, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401640/ https://www.ncbi.nlm.nih.gov/pubmed/25884288 http://dx.doi.org/10.1371/journal.pbio.1002125 |
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