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MAGMA: Generalized Gene-Set Analysis of GWAS Data

By aggregating data for complex traits in a biologically meaningful way, gene and gene-set analysis constitute a valuable addition to single-marker analysis. However, although various methods for gene and gene-set analysis currently exist, they generally suffer from a number of issues. Statistical p...

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Detalles Bibliográficos
Autores principales: de Leeuw, Christiaan A., Mooij, Joris M., Heskes, Tom, Posthuma, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401657/
https://www.ncbi.nlm.nih.gov/pubmed/25885710
http://dx.doi.org/10.1371/journal.pcbi.1004219