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The Universal Statistical Distributions of the Affinity, Equilibrium Constants, Kinetics and Specificity in Biomolecular Recognition

We uncovered the universal statistical laws for the biomolecular recognition/binding process. We quantified the statistical energy landscapes for binding, from which we can characterize the distributions of the binding free energy (affinity), the equilibrium constants, the kinetics and the specifici...

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Detalles Bibliográficos
Autores principales: Zheng, Xiliang, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401658/
https://www.ncbi.nlm.nih.gov/pubmed/25885453
http://dx.doi.org/10.1371/journal.pcbi.1004212