Na(+)/H(+) Exchanger Isoform 1-Induced Osteopontin Expression Facilitates Cardiomyocyte Hypertrophy

Enhanced expression and activity of the Na(+)/H(+) exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin (OPN) expression in models of cardiac hypertrophy (CH), and the mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamed, Iman A., Gadeau, Alain-Pierre, Fliegel, Larry, Lopaschuk, Gary, Mlih, Mohamed, Abdulrahman, Nabeel, Fillmore, Natasha, Mraiche, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401699/
https://www.ncbi.nlm.nih.gov/pubmed/25884410
http://dx.doi.org/10.1371/journal.pone.0123318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401699/
https://www.ncbi.nlm.nih.gov/pubmed/25884410
http://dx.doi.org/10.1371/journal.pone.0123318

Ejemplares similares