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The Single Nucleotide Polymorphism Gly482Ser in the PGC-1α Gene Impairs Exercise-Induced Slow-Twitch Muscle Fibre Transformation in Humans

PGC-1α (peroxisome proliferator-activated receptor γ co-activator 1α) is an important regulator of mitochondrial biogenesis and a master regulator of enzymes involved in oxidative phosphorylation. Recent evidence demonstrated that the Gly482Ser single nucleotide polymorphism (SNP) in the PGC-1α gene...

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Detalles Bibliográficos
Autores principales: Steinbacher, Peter, Feichtinger, René G., Kedenko, Lyudmyla, Kedenko, Igor, Reinhardt, Sandra, Schönauer, Anna-Lena, Leitner, Isabella, Sänger, Alexandra M., Stoiber, Walter, Kofler, Barbara, Förster, Holger, Paulweber, Bernhard, Ring-Dimitriou, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401702/
https://www.ncbi.nlm.nih.gov/pubmed/25886402
http://dx.doi.org/10.1371/journal.pone.0123881