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Phase 1 Study of Pandemic H1 DNA Vaccine in Healthy Adults

BACKGROUND: A novel, swine-origin influenza A (H1N1) virus was detected worldwide in April 2009, and the World Health Organization (WHO) declared a global pandemic that June. DNA vaccine priming improves responses to inactivated influenza vaccines. We describe the rapid production and clinical evalu...

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Detalles Bibliográficos
Autores principales: Crank, Michelle C., Gordon, Ingelise J., Yamshchikov, Galina V., Sitar, Sandra, Hu, Zonghui, Enama, Mary E., Holman, LaSonji A., Bailer, Robert T., Pearce, Melissa B., Koup, Richard A., Mascola, John R., Nabel, Gary J., Tumpey, Terrence M., Schwartz, Richard M., Graham, Barney S., Ledgerwood, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401709/
https://www.ncbi.nlm.nih.gov/pubmed/25884189
http://dx.doi.org/10.1371/journal.pone.0123969